Proefschrift Kerklaan
PEPaNIC trial
SUPPLEMENTARY FIGURES
Early PN
Late PN
Enteral
Parenteral
Total
100
100
100
75
75
75
50
50
50
Total Energy 25
(kcal/kg/day)
25
25
0
0
0
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
2.5
2.5
2.5
2
2
2
1.5
1.5
1.5
Protein
1
1
1
(gram/kg/day)
0.5
0.5
0.5
0
0
0
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
7
12.5
12.5
12.5
10
10
10
7.5
7.5
7.5
5
5
5
(gram/kg/day)
Carbohydrates
2.5
2.5
2.5
0
0
0
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
0 0.5 1 1.5 2 2.5 3 3.5
0 0.5 1 1.5 2 2.5 3 3.5
0 0.5 1 1.5 2 2.5 3 3.5
Fat
(gram/kg/day)
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
d1
d4
d8
d12
d16
Day after Inclusion
Day after Inclusion
Day after Inclusion
No. in PICU Late PN Early PN 723 717
93 63
723 717
216 159
139 103
399 348
723 717
93 63
216 159
139 103
399 348
93 63
216 159
139 103
399 348
Supplementary Figure 1. Caloric and macronutrient intake per kg Daily amount of energy in kcal/kg/day, and the daily amounts of substrates in g/kg/day, for the first 16 days of pediatric intensive care unit (PICU) stay provided by the enteral route, the parenteral route or both (total). Bars represent the mean and the whiskers represent the standard error of the mean (SEM). The red bars represent the late parenteral nutrition (PN) group; the blue bars represent the early PN group.
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